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Intern Med ; 61(22): 3439-3444, 2022 Nov 15.
Article in English | MEDLINE | ID: covidwho-2022248

ABSTRACT

We herein report a case of cerebral infarct in a patient with coronavirus disease 2019 (COVID-19) infection who died of aspiration pneumonia. The postmortem examination of the brain revealed embolic infarct with negative findings on quantitative reverse transcription polymerase chain reaction (qRT-PCR) as well as immunohistochemistry to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The systemic examination only revealed low copy numbers of SARS-CoV-2 in the bronchus. This is the first and so far only autopsy case of COVID-19 infection with pathologic and virologic findings of the postmortem brain in Japan.


Subject(s)
COVID-19 , Humans , COVID-19/complications , SARS-CoV-2 , Autopsy , COVID-19 Testing , Cerebral Infarction/complications
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